Add Understanding Average Glucose, Standard Deviation, CV, and Blood Sugar Variability
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<br>What do these numbers mean, what’s the target, and how can they provide insight into better diabetes management? [Glucose monitoring](https://www.answers.com/search?q=Glucose%20monitoring) is one of the most important tools in diabetes. Just like a speedometer in a car, [GlycoMode Blood Sugar Supplement](https://hull.kr/free/30) glucose data helps inform key actions in diabetes - take more or less medication, [GlycoMode supplement](https://cepem.wiki/index.php/GlycoMode:_Revolutionizing_Glycobiology_Research) change food choices or timing, exercise, and [devcraft-dot.tech](https://devcraft-dot.tech/madelinedaughe) more. Most of us think of glucose data in an immediate sense for [guiding therapy](https://www.travelwitheaseblog.com/?s=guiding%20therapy) decisions: "How much insulin should I take right now? " However, it also helps inform longer-term patterns: "My blood sugar has been consistently high after breakfast for the past two weeks; why might that be and what can be done about it? Last December, we covered time-in-range in two articles - Kelly Close and Adam interviewed 15 experts and then wrote "What do experts think about goals? " and Adam took a personal look at all his CGM data and wrote, with lots of advice from many of the same experts, "What’s an achievable time-in-range goal with diabetes?<br>
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<br>" This article is about the first three statistics: average (mean) glucose, SD, and CV. The information below on mean glucose, SD, and CV is relevant to all readers who monitor their glucose, though it’s often not available on the device itself - you must usually download your meter or CGM to a paired app or computer software. At the end of this article, we’ve listed options for some of the most commonly used devices. In this piece, we’ve turned yet again to the experts! This article integrates feedback from a dozen of the world’s smartest thinkers (endocrinologists, educators, researchers) on glucose monitoring and glucose variability. What is mean glucose? What’s a good target? "Mean glucose" is another way of saying "average glucose." It’s an overall measure of blood sugars over a period of time, offering a single high-level view of where glucose has been. A lower mean glucose often indicates fewer high blood sugars; however, it can also indicate a lot of low blood sugars (hypoglycemia) are occurring.<br>
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<br>Many experts look for a mean glucose of less than 154 mg/dl in adults with diabetes, which approximates to an A1C less than 7% (the target in the USA). In kids, the target is slightly higher: an A1C less than 7.5%, which corresponds to mean glucose of 170 mg/dl. However, these are population averages. As we’ve discussed previously, in "What’s a Normal A1C? When is it Misleading? ", the relationship between A1C and mean glucose can vary quite a bit from person to person. Still, aiming for a mean glucose of less than 154 mg/dl in adults and less than 170 mg/dl in kids is a good starting point for most - check with your healthcare team, of course, if you are making major changes. Over the long term, the goal is the lowest possible average glucose without frequent, prolonged, or severe hypoglycemia, based on evidence from the DCCT and UKPDS. For those wondering, in people without diabetes, mean glucose is typically 100 mg/dl or less, which corresponds to an A1C of less than 5.7% (the cutoff for diagnosing prediabetes).<br>
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<br>The cutoff for diagnosing diabetes is an A1C of 6.5%, corresponding to a mean glucose of roughly 135 mg/dl. Knowing one’s average glucose over a period of time is kind of like knowing the average temperature over the course of a month or the average speed over a road trip - it doesn’t tell you what happens in different moments or what to change. However, mean glucose can be a useful flag that high or low blood sugars are common. A mean glucose of 225 mg/dl could indicate a lot of high blood sugars are happening, implying changes are needed - e.g., a higher medication dose, different food choices. Dr. Irl Hirsch also pointed out that this kind of average could imply medication doses are being missed, especially for those with type 1. Many experts brought up a caveat, however: a mean glucose of 225 mg/dl can still hide a lot of low [GlycoMode Blood Sugar support](https://falone.eu/index.php?title=Revolutionizing_Glycoanalysis:_The_Emergence_Of_Glyco_Mode) sugars!<br>
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<br>Before making changes to increase medication, it’s important to make sure hypoglycemia is not occurring - ideally with professional or personal CGM. If mean glucose is 100 mg/dl and someone is experiencing many low blood sugars (hypoglycemia) every day of the week, changes are needed too - e.g., closer attention to when the hypoglycemia is happening in order to determine the best action, such as differently timed exercise or a lower medication dose. What are SD and CV? Why do they matter? SD and CV are two statistical values that provide a different lens to look at glucose variability, similar in a way to time-in-range (TIR) numbers. "SD" is shorthand for "standard deviation," which is a measure of the spread in glucose readings around the average - some call this the variation. For example, if someone has been bouncing around between many highs and/or many lows on a given day, they will have a larger SD. On the other hand, if someone is having a pretty stable day, she will have a lower SD.<br>
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